Applying security to folder according to its username

Hello dear gurus. I have a question. I couldn't find anything on the web..

So I have about 600+ folders. Each folder corresponding to username in domain whom I must grant access to it.

For example: within "Share" folder I have below listed folders

• John Smith
• Will Smith
• Sundra Bullock
• Mark Whalberg

So, John smith must be able to see only what within "John Smith" folder, and when he double click any other folder "Access denied"  error message must appear. The same for Will Smith ... The same for Sundra Bullock ... And any 600+ folders.

Is possible to do ????